The effect of the combination of caffeine and taurine of different concentrations on activated B-cells

Abstract

Caffeinated drinks are popular because of their mood- and performance-enhancing effects. Energy drinks in particular are advertised with these properties, with the content of caffeine and taurine being a central component of these products. However, little is known about the influence of taurine and caffeine on immune cells. This article answers the following research question: “How high is the effect of the combination of caffeine and taurine of different concentrations on activated B-cells”.
Immunoglobulin production is a measure of B-cell activity. This property is determined in mouse B-cells. For this purpose, these cells are taken from the spleen of mice, induced with CD40/IL4 and the activity is checked with the aid of an immunoglobulin ELISA. Low doses of taurine and caffeine in combination do not cause any significant change in immunoglobulin production, whereas high doses (4 or 40 mg / ml) lead to cell death.